As much as possible, eat cold-water fish. Research has linked Omega-3 fatty acids found in salmon, tuna, and other cold-water fish to an easing of depression.Oasis Dating Get enough rest. Getting enough sleep leads to better health and refreshes your mind so you can fight off depression. When you're tired, depression and anxiety symptoms are much more prevalent. If insomnia is a problem for you, meditate before bed or discuss your problem with your doctor, who may prescribe a sleep aid.